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Results for "

urea linker

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

2

Click Chemistry

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147287
    Glu-urea-Glu-NHS ester

    		PSMA Cancer
    Glu-urea-Glu-NHS ester (compound 21) is an activated N-hydroxysuccinamide (NHS) ester of Glu-urea-Glu which can be used as a pharmacophore for linking with prostate specific membrane antigen (PSMA) inhibitors .
    Glu-urea-Glu-NHS ester
  • HY-43869
    Vipivotide tetraxetan Ligand-Linker Conjugate

    PSMA-617 Ligand-linker Conjugate

    		 ADC Linker Cancer
    Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is a complex composed of pharmacophore group Glutamate-urea-Lysine peptide coupling linker, which can be used to synthesize Vipivotide tetraxetan (PSMA-617). Glutamate-urea-Lysine selectively binds to prostate-specific membrane antigen (PSMA) .
    Vipivotide tetraxetan Ligand-Linker Conjugate
  • HY-117410
    Vipivotide tetraxetan
    5+ Cited Publications

    PSMA-617

    		 Drug-Linker Conjugates for ADC Cancer
    Vipivotide tetraxetan (PSMA-617) is a high potent prostate-specific membrane antigen (PSMA) inhibitor, with a Ki of 0.37 nM. Vipivotide tetraxetan (PSMA-617) is designed consisting of three components: the pharmacophore Glutamate-urea-Lysine, the chelator DOTA able to complex both 68Ga or 177Lu, and a linker connecting these two entities. Glutamate-urea-Lysine is the selective pharmacophore to bind to prostate specific membrane antigen.
    Vipivotide tetraxetan
  • HY-108379
    Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid

    		ADC Linker Cancer
    Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    Boc-C2-Urea-bis(Boc)-C4-Urea-4-phenylacetic acid
  • HY-134749
    Propargyl-PEG2-urea-C3-triethoxysilane

    		PROTAC Linkers Cancer
    Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-urea-C3-triethoxysilane is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargyl-PEG2-urea-C3-triethoxysilane
  • HY-145889
    LC kinetic stabilizer-1

    		Others Others
    LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL * and WIL-FL * T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer .
    LC kinetic stabilizer-1
  • HY-146122
    ATX inhibitor 19

    		Phosphodiesterase (PDE) Cancer
    ATX inhibitor 19 (compound 22) is a potent ATX (autotaxin) inhibitor, with an IC50 of 156 nM .
    ATX inhibitor 19
  • HY-151769
    TCO-PEG2-Sulfo-NHS ester-EDC Urea

    		ADC Linker Others
    TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent containing an azide group. TCO-PEG2-Sulfo-NHS ester is a PEG linker containing a TCO moiety and a sulfo-NHS ester moiety. The sulfo group makes this molecule soluble in waqueous buffer. This reagent can be used to label antibodies, proteins and other primary amine-containing macromolecules with TCO moiety. Reagent grade, for research use only . TCO-PEG2-Sulfo-NHS ester-EDC Urea is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
    TCO-PEG2-Sulfo-NHS ester-EDC Urea
  • HY-146124
    ATX inhibitor 21

    		Phosphodiesterase (PDE) Cancer
    ATX inhibitor 21 (compound 8) is a potent ATX (autotaxin) inhibitor, with an IC50 of 3490 nM .
    ATX inhibitor 21
  • HY-146123
    ATX inhibitor 20

    		Phosphodiesterase (PDE) Cancer
    ATX inhibitor 20 (compound 24) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.3 nM .
    ATX inhibitor 20

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